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Mpox vaccine

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Quick facts
Recommended for
Age 18+ with increased risk of exposure
Frequency
2 doses

What is mpox?

Mpox, previously known as monkeypox, is an infectious disease caused by a virus closely related to the virus responsible for smallpox.

There are two types of mpox, and both spread through various means including close contact with infected individuals, which can include intimate or sexual contact, as well as exposure to contaminated objects that have been in contact with an infected person. Contaminated objects and materials may include clothing, towels, bedding or intimate products. Additionally, transmission can occur through direct encounters with small wild animals in West or Central Africa, involving exposure to their fluids or waste, or through scratches or bites.

Individuals affected by mpox typically develop a rash, often appearing on areas such as the hands, feet, chest, face, mouth, or on or near the genital region. This rash progresses through stages, initially appearing as pimples or blister-like lesions that can be painful or itchy, and then progress to scabs before healing.

Other symptoms may include fever, chills, swollen lymph nodes, fatigue, muscle aches, backache, headache and respiratory issues, such as sore throat, nasal congestion or coughing.

People may experience all or only a few symptoms. These symptoms generally begin within 21 days of exposure to the virus.

Frequently Asked Questions

  • The U.S. Food and Drug Administration approved an mpox vaccine for use in the United States, called JYNNEOS, which is approved for use in individuals 18 years of age and older.

    To learn more about the mpox vaccine from the CDC, visit the CDC website.

    • Vaccination is key in preventing the spread of mpox. The CDC recommends vaccination for those ages 18 years and older at risk for mpox infection including those who:

    • have a known or suspected exposure to someone with mpox
    • had a sex partner in the past 2 weeks who was diagnosed with mpox
    • are a gay, bisexual, or other man who has sex with men, transgender or nonbinary people who in the past 6 months have had one of the following:
      • A new diagnosis of ≥1 sexually transmitted disease
      • More than one sex partner
      • Sex at a commercial sex venue
      • Sex in association with a large public event in a geographic area where mpox transmission is occurring
    • have a sex partner with any of the above risks or those who anticipate experiencing any of the above scenarios
    • are immunocompromised as a result of a condition or treatment for other disease states
    • are an emergency service worker or laboratory personnel who works with orthopoxviruses
    • Persons who have experienced severe allergic reactions to any component of the mpox vaccine.
    • Before getting the mpox vaccine, you should let your healthcare provider know if you’ve had an allergic reaction to any vaccine and if you’ve had an allergic reaction to the antibiotics gentamicin or ciprofloxacin, or chicken or egg protein.
  • The most common side effects include pain, redness, and itching at the injection spot. People may also experience fever, tiredness, headache, nausea, chills, and muscle pain.

If you believe you have a medical emergency, please call 911.

References:

U.S. Centers for Disease Control and Prevention (CDC). Mpox. 15 March 2024. https://www.cdc.gov/poxvirus/mpox/about/index.html. Accessed 03/20/2024.


U.S. Centers for Disease Control. ACIP Recommendations. 29 Feb. 2024. https://www.cdc.gov/vaccines/acip/recommendations.html#meeting-recommendations. Accessed 03/21/2024.


U.S Centers for Disease Control and Prevention (CDC). Mpox: Signs and Symptoms. 15 March 2024. https://www.cdc.gov/poxvirus/mpox/symptoms/index.html. Accessed 03/21/2024.


U.S Centers for Disease Control and Prevention (CDC). Mpox: How It Spreads. 1 March 2024. https://www.cdc.gov/poxvirus/mpox/if-sick/transmission.html. Accessed 03/21/2024.


U.S Centers for Disease Control and Prevention (CDC). Mpox Vaccine Recommendations. 21 Aug. 2023. https://www.cdc.gov/poxvirus/mpox/vaccines/vaccine-recommendations.html. Accessed 03/21/2024.


JYNNEOS [package insert]. https://bavariannordic.io/uploads/jynneos-pi.pdf. Hellerup, Denmark: Bavarian Nordic A/S. Sept. 2023. Accessed 03/21/2024.


U.S Centers for Disease Control and Prevention (CDC). JYNNEOS Vaccine. 1 Sept. 2023. https://www.cdc.gov/poxvirus/mpox/interim-considerations/jynneos-vaccine.html. Accessed 03/21/2024.